SCHEMBL7754564

SCHEMBL7754564

C=CC(=O)NCc1ccc(S(=O)(=O)NC(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
NPSR1 Q6W5P4 1/20 0.55
NAMPT P43490 1/20 0.54
TGM2 P21980 1/20 0.54
GAA P10253 2/20 0.52
MAPT P10636 2/20 0.52
ADAMTS4 O75173 2/20 0.49
MMP13 P45452 1/20 0.49
POLB P06746 1/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396211 0.89 MAPT (0.53) ALDH1A1NAMPTTGM2GAAMAPT
SCHEMBL7751005 0.84 CCR1 (0.48) ALDH1A1NPSR1NAMPTTGM2KDM4E
SCHEMBL394379 0.84 TGM2 (0.58) ALDH1A1NAMPTTGM2GAAMAPT
SCHEMBL7754150 0.84 ALDH1A1 (0.57) ALDH1A1TGM2GAAMAPTLMNA
SCHEMBL393582 0.82 ALDH1A1 (0.57) ALDH1A1TGM2LMNA
SCHEMBL398194 0.81 NAMPT (0.54) ALDH1A1NPSR1NAMPTTGM2MAPT
SCHEMBL7784363 0.81 ALDH1A1 (0.54) ALDH1A1NPSR1NAMPTTGM2MAPT
SCHEMBL398016 0.80 NAMPT (0.55) ALDH1A1NAMPTTGM2GAAMAPT
SCHEMBL2723034 0.79 TGM2 (0.63) ALDH1A1TGM2GAAMAPTPOLB
SCHEMBL7785815 0.79 TGM2 (0.55) ALDH1A1NAMPTTGM2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed