Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164417 | 0.80 | MEN1 (0.48) | P2RX3HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7432141 | 0.78 | POLB (0.57) | P2RX3CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL169682 | 0.78 | KMT2A (0.55) | P2RX3HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6393425 | 0.76 | ALDH1A1 (0.52) | P2RX3ALDH1A1RAB9AROCK2 | |
| SCHEMBL3293477 | 0.76 | ALDH1A1 (0.55) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL20653314 | 0.75 | ROCK2 (0.46) | P2RX3CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL20641288 | 0.75 | SRD5A2 (0.46) | P2RX3CYP3A4ALDH1A1ROCK2SMN1; SMN2 | |
| SCHEMBL20641265 | 0.75 | ROCK2 (0.48) | P2RX3CYP3A4ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6478838 | 0.75 | P2RX3 (0.40) | P2RX3CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6489908 | 0.75 | P2RX3 (0.40) | P2RX3CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001035947-A2 | TREATING WASTING SYNDROMES WITH ARYLOXY PROPANOLAMINES | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |