Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1436075 | 0.67 | CYP2D6 (0.50) | TDP1POLBLMNAMEN1KMT2A | |
| SCHEMBL7527763 | 0.66 | POLB (0.43) | POLBLMNAMEN1KMT2AMAPT | |
| SCHEMBL18129367 | 0.66 | CYP1A2 (0.49) | TDP1POLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL7535112 | 0.66 | POLB (0.47) | TDP1POLBTHRBL3MBTL1RECQL | |
| SCHEMBL5185226 | 0.66 | CYP1A2 (0.49) | TDP1POLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL4423068 | 0.66 | TDP1 (0.40) | TDP1POLBTHRBL3MBTL1LMNA | |
| SCHEMBL1145559 | 0.65 | TP53 (0.48) | TDP1SMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL6328103 | 0.65 | NOS2 (0.41) | TDP1POLBTHRBL3MBTL1RECQL | |
| SCHEMBL7268486 | 0.65 | HPGD (0.58) | TDP1POLBTHRBRECQLLMNA | |
| SCHEMBL224923 | 0.65 | TP53 (0.52) | TDP1RECQLSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064271-A1 | 2- (2-ARYLTHIOETHYL)AMINO]-4-AMINO-1,3,5-TRIAZINES USED AS HERBICIDES | BAYER AG (DE) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048877-A1 | 2-[(2-ARYLTHIOETHYL)AMINO]-4-AMINO-1,3,5-TRIAZINES USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-30 | — | — | WO | disclosed |