SCHEMBL7751839

SCHEMBL7751839

CO/N=C(/C(=O)O)c1ccccc1COC/C=N/OCCc1ccnc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.36
CYP1A2 P05177 2/20 0.36
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CASP1 P29466 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FLT1 P17948 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753079 0.75 HIF1A (0.45) HIF1AALDH1A1GAAMAPTHPGD
SCHEMBL7752768 0.74 HIF1A (0.40) HIF1A
SCHEMBL7751843 0.73 HIF1A (0.37) HIF1AMEN1KMT2AALDH1A1POLB
SCHEMBL7752188 0.73 HIF1A (0.39) HIF1A
SCHEMBL7752757 0.70 CYP1A2 (0.36) CYP1A2ALDH1A1
SCHEMBL8210930 0.69 HIF1A (0.43) HIF1A
SCHEMBL8209643 0.69 HIF1A (0.43) HIF1A
SCHEMBL8209463 0.69 PPARG (0.34) HIF1AKMT2ANPC1ALDH1A1HPGD
SCHEMBL7751837 0.69 HIF1A (0.34) HIF1A
SCHEMBL7747803 0.69 HIF1A (0.34) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070052-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 2001-01-24 EP disclosed
WO-1999051579-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 1999-10-14 WO disclosed