SCHEMBL7752188

SCHEMBL7752188

CO/N=C(/C(=O)O)c1ccccc1COC/C=N/Oc1ncccc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.39
SSTR4 P31391 10/20 0.37
SSTR1 P30872 4/20 0.36
CTNNB1 P35222 1/20 0.34
WNT3A P56704 1/20 0.34
RBP4 P02753 1/20 0.34
TTR P02766 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752768 0.76 HIF1A (0.40) HIF1A
SCHEMBL7753079 0.76 HIF1A (0.45) HIF1A
SCHEMBL7752186 0.76 L3MBTL1 (0.38) SSTR4CTNNB1WNT3ARBP4TTR
SCHEMBL8370620 0.76 HIF1A (0.46) HIF1ASSTR4SSTR1
SCHEMBL8370616 0.76 HIF1A (0.46) HIF1ASSTR4SSTR1
SCHEMBL7751839 0.73 HIF1A (0.36) HIF1A
SCHEMBL18281648 0.70 SGMS2 (0.40) SSTR4SSTR1CTNNB1WNT3A
SCHEMBL18281647 0.70 SGMS2 (0.40) SSTR4SSTR1CTNNB1WNT3A
SCHEMBL7751843 0.70 HIF1A (0.37) HIF1A
SCHEMBL8209643 0.70 HIF1A (0.43) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070052-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 2001-01-24 EP disclosed
WO-1999051579-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 1999-10-14 WO disclosed