Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430667 | 0.84 | S1PR1 (0.37) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL7426895 | 0.81 | S1PR1 (0.36) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL29338673 | 0.81 | S1PR1 (0.37) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL15080876 | 0.81 | S1PR1 (0.37) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL16809676 | 0.79 | S1PR1 (0.39) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL2112705 | 0.79 | S1PR1 (0.39) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL1577276 | 0.79 | AGBL2 (0.37) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL661676 | 0.78 | NOS3 (0.46) | AGBL2 | |
| SCHEMBL18489099 | 0.78 | S1PR1 (0.35) | S1PR1S1PR3SMN1; SMN2HTTKMT2A | |
| SCHEMBL5733354 | 0.76 | S1PR1 (0.34) | S1PR1S1PR3SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| US-6114336-A | Cosmetic composition containing a neuropeptide Y receptor antagonist | SANOFI (FR) | 2000-09-05 | — | — | US | disclosed |
| US-5827853-A | MIXTURE CONTAINING PRODUCT FROM FERMENTATION BY STREPTOMYCES FOR TOPICAL APPLICATION TO SKIN OR HAIR, TO IMPROVE TEXTURE, SURFACE SMOOTHNESS, FIRMNESS | SANOFI (FR) | 1998-10-27 | — | — | US | disclosed |