Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752073 | 0.95 | FFAR1 (0.33) | CASP1HSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL7750623 | 0.90 | SMN1; SMN2 (0.39) | CASP1HSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL7750624 | 0.86 | SMN1; SMN2 (0.36) | CASP1HSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL16691418 | 0.85 | L3MBTL1 (0.41) | CASP1HSD17B10LMNAHPGDNPC1 | |
| SCHEMBL3519610 | 0.85 | L3MBTL1 (0.45) | CASP1HSD17B10LMNAHPGDNPC1 | |
| SCHEMBL11823176 | 0.84 | ALDH1A1 (0.34) | ALDH1A1HPGDTDP1L3MBTL1EPHX2 | |
| SCHEMBL6996519 | 0.81 | DRD2 (0.37) | ALDH1A1LMNAHPGDL3MBTL1TSHR | |
| SCHEMBL6544463 | 0.81 | L3MBTL1 (0.41) | CASP1HSD17B10ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7752058 | 0.79 | L3MBTL1 (0.42) | CASP1HSD17B10LMNAHPGDNPC1 | |
| SCHEMBL6139367 | 0.79 | TSHR (0.38) | CASP1HSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242607-B1 | SUCH AS 4-CYANO-4-(3,4-DICHLOROPHENYL)HEPTANEDIOIC ACID USED AS ANTAGONISTS OF NEUROKININES | SANOFI-SYNTHELABO (FR) | 2001-06-05 | — | — | US | disclosed |
| US-6008360-A | Substituted 3-aryl-3-carboxyalkyl glutaramides, method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation, and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines | SANOFI-SYNTHELABO (FR) | 1999-12-28 | — | — | US | disclosed |