Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752071 | 0.95 | CASP1 (0.35) | NPC1CASP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL7750624 | 0.91 | SMN1; SMN2 (0.36) | CYP2C19CASP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL6544463 | 0.86 | L3MBTL1 (0.41) | FFAR1CYP2C19CASP1HSD17B10ALDH1A1 | |
| SCHEMBL7750623 | 0.86 | SMN1; SMN2 (0.39) | CASP1HSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL6139367 | 0.86 | TSHR (0.38) | FFAR1CYP2C19CASP1HSD17B10ALDH1A1 | |
| SCHEMBL16691418 | 0.81 | L3MBTL1 (0.41) | NPC1CASP1HSD17B10LMNAKDM4E | |
| SCHEMBL3519610 | 0.81 | L3MBTL1 (0.45) | NPC1CASP1HSD17B10LMNAKDM4E | |
| SCHEMBL7752063 | 0.81 | L3MBTL1 (0.38) | FFAR1CYP2C19CASP1HSD17B10ALDH1A1 | |
| SCHEMBL11823176 | 0.80 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1HPGDTOP2A | |
| SCHEMBL7749391 | 0.80 | MIF (0.37) | FFAR1CYP2C19ALDH1A1ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242607-B1 | SUCH AS 4-CYANO-4-(3,4-DICHLOROPHENYL)HEPTANEDIOIC ACID USED AS ANTAGONISTS OF NEUROKININES | SANOFI-SYNTHELABO (FR) | 2001-06-05 | — | — | US | disclosed |
| US-6008360-A | Substituted 3-aryl-3-carboxyalkyl glutaramides, method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation, and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines | SANOFI-SYNTHELABO (FR) | 1999-12-28 | — | — | US | disclosed |