SCHEMBL7752087

SCHEMBL7752087

CC(C)(C)c1[c]cccc1-c1ccccc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA2 P00918 1/20 0.34
TRPA1 O75762 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125906 0.81 CA2 (0.41) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL10583003 0.81 ALDH1A1 (0.41) ALDH1A1TDP1
SCHEMBL6691244 0.81 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CA2TRPA1
SCHEMBL1194484 0.78 ALDH1A1 (0.55) ALDH1A1TSHRTDP1CA2TRPA1
SCHEMBL3539990 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL11762666 0.77 ALDH1A1 (0.34) ALDH1A1TSHRTDP1CA2TRPA1
SCHEMBL5551926 0.77 CA1 (0.35) ALDH1A1TSHRCA2TRPA1GABRA1
SCHEMBL545684 0.76 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2TRPA1
Phosphine SCHEMBL2238711 0.76 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2TRPA1
SCHEMBL6131760 0.76 PTGS2 (0.35) ALDH1A1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066229-A1 OLIGOMERIZATION OF PROPYLENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-10 EP disclosed
US-6063881-A USING COBALT COMPLEXES OF PYRIDINEBIS(IMINES) AS CATALYSTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-16 US disclosed
WO-1999051550-A1 OLIGOMERIZATION OF PROPYLENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-10-14 WO disclosed