Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370525 | 0.84 | MAPT (0.47) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL4304719 | 0.78 | ACHE (0.50) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL10865232 | 0.78 | PPARG (0.51) | L3MBTL1ACHEMAPTCA9MEN1 | |
| SCHEMBL18925030 | 0.78 | PTGS2 (0.50) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL4098658 | 0.77 | PTGS2 (0.54) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL10110894 | 0.77 | PTGS2 (0.54) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL2618698 | 0.77 | PTGS2 (0.54) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL10415398 | 0.76 | PPARG (0.50) | L3MBTL1ACHEMAPTCA9MEN1 | |
| SCHEMBL17472292 | 0.75 | PTGS2 (0.52) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL12659351 | 0.75 | PTGS2 (0.52) | PTGS2L3MBTL1ACHEMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042245-A1 | NEUROTROPHIC BICYCLIC DIAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |