Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10110894 | 0.77 | PTGS2 (0.54) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL2618698 | 0.77 | PTGS2 (0.54) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL4098658 | 0.77 | PTGS2 (0.54) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL12659351 | 0.75 | PTGS2 (0.52) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL7752210 | 0.75 | PTGS2 (0.52) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL2007010 | 0.75 | TUBB4A (0.58) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL24779578 | 0.73 | PTGS2 (0.50) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL9136813 | 0.73 | PTGS2 (0.50) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL23682245 | 0.73 | PTGS2 (0.50) | PTGS2L3MBTL1ACHEMAPTCYP3A4 | |
| SCHEMBL18925030 | 0.73 | PTGS2 (0.50) | PTGS2L3MBTL1ACHEMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160022642-A1 | Compounds Useful for Promoting Protein Degradation and Methods Using Same | YALE UNIVERSITY | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022642-A1 | Compounds Useful for Promoting Protein Degradation and Methods Using Same | AR, SHBG, PSMG3 | PTGS2 3176/4885L3MBTL1 1936/4885ACHE 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.