Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1200041 | 1.00 | EGLN1 (0.60) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL7194377 | 1.00 | EGLN1 (0.60) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL7095069 | 1.00 | EGLN1 (0.60) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL6421948 | 0.91 | EGLN1 (0.50) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28609907 | 0.89 | LMNA (0.48) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Glutarate SCHEMBL6333785 | 0.88 | SLC22A6 (0.65) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Adipic Acid SCHEMBL6402459 | 0.88 | LMNA (0.65) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Adipic Acid SCHEMBL874846 | 0.88 | LMNA (0.65) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Sebacic Acid SCHEMBL7054977 | 0.85 | TSHR (0.67) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Propene SCHEMBL7058438 | 0.85 | TSHR (0.67) | LMNAABCC4MAPTOR51E2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617934-B2 | Low noise biodegradable breathable films | OMYA INTERNATIONAL AG (CH) | 2026-05-05 | — | — | US | claimed |
| CN-119920823-A | Electrode, preparation method thereof and lithium ion battery | 重庆太蓝新能源有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119842159-A | Combined cover for infusion container and preparation method thereof | 崇州君健塑胶有限公司 | 2025-04-18 | — | — | CN | claimed |
| WO-2025065827-A1 | PREPARATION METHOD FOR COMPOSITE CERAMIC SEPARATOR, COMPOSITE CERAMIC SEPARATOR AND BATTERY | 重庆太蓝新能源有限公司 | 2025-04-03 | — | — | WO | claimed |
| US-20250092578-A1 | PLA FIBRES AND NONWOVENS MADE THEREOF | TOTALENERGIES CORBION BV (NL) | 2025-03-20 | — | — | US | claimed |
| EP-4175998-B1 | LOW NOISE BIODEGRADABLE BREATHABLE FILMS | OMYA INT AG (CH) | 2025-03-19 | — | — | EP | claimed |
| CN-114507431-B | Low-printing-temperature polycarbonate modified material for 3D printing, preparation method thereof and printing wire | 中国石油化工股份有限公司 | 2025-03-04 | — | — | CN | claimed |
| US-20250051539-A1 | CALCIUM CARBONATE-COMPRISING MATERIAL WITH HIGH BIO-BASED CARBON CONTENT FOR POLYMER FORMULATIONS | OMYA INTERNATIONAL AG (CH) | 2025-02-13 | — | — | US | claimed |
| CN-119371630-A | Degradable bio-based TPU (thermoplastic polyurethane) for agricultural mulching film and preparation method thereof | 山东一诺威聚氨酯股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| US-20240409719-A1 | PRECIPITATED CALCIUM CARBONATE WITH HIGH BIO-BASED CARBON CONTENT FOR POLYMER FORMULATIONS | OMYA INTERNATIONAL AG (CH) | 2024-12-12 | — | — | US | claimed |
| CN-114728102-A | Method for producing an intraluminal endoprosthesis having a biodegradable sheath | 科特罗尼克有限公司 | 2022-07-08 | — | — | CN | claimed |
| WO-2022147330-A1 | MELT EXTRUSION OF HEMP-BASED THERMOPLASTICS | NORTH CAROLINA STATE UNIVERSITY (US) | 2022-07-07 | — | — | WO | claimed |
| US-20220204774-A1 | MELT EXTRUSION OF HEMP-BASED THERMOPLASTICS | NORTH CAROLINA STATE UNIVERSITY | 2022-06-30 | — | — | US | claimed |
| CN-114585667-A | Oriented film of binary polymer composition | 伍德利有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-114316181-A | High-resilience biodegradable polyester foam material and preparation method and application thereof | 美瑞新材料创新中心(山东)有限公司 | 2022-04-12 | — | — | CN | claimed |
| EP-3807345-A1 | POLYMERIC PRODUCTS | Stichting Wageningen Research (NL) | 2021-04-21 | — | — | EP | claimed |
| EP-3581608-A1 | POLYMERIC PRODUCTS | Stichting Wageningen Research (NL) | 2019-12-18 | — | — | EP | claimed |
| EP-3297949-A1 | ORGANO-MODIFIED LAYERED DOUBLE HYDROXIDES AND COMPOSITE POLYMER MATERIALS COMPRISING SAME | Centre National De La Recherche Scientifique (FR) | 2018-03-28 | — | — | EP | claimed |
| CN-106519597-A | A matte aluminum plated film | 无锡三帝特种高分子材料有限公司 | 2017-03-22 | — | — | CN | claimed |
| EP-0490454-B1 | Alkenyl succinimides as luboil additives | SHELL INT RESEARCH (NL) | 1993-11-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617934-B2 | Low noise biodegradable breathable films | COL2A1, COL1A1, CA7 | SLC6A2 2671/4885SLC6A4 2322/4885EGLN1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.