Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752712 | 0.91 | CCKAR (0.73) | CCKARCCKBR | |
| SCHEMBL8089891 | 0.82 | CCKAR (0.54) | CCKARCCKBR | |
| SCHEMBL8783591 | 0.81 | CCKBR (0.52) | CCKARCCKBR | |
| SCHEMBL7747691 | 0.78 | CCKBR (1.00) | CCKARCCKBR | |
| SCHEMBL7752996 | 0.76 | CCKBR (0.47) | CCKARCCKBR | |
| SCHEMBL3890199 | 0.76 | CCKAR (1.00) | CCKARCCKBR | |
| SCHEMBL8095851 | 0.75 | ACE (0.46) | CCKARCCKBR | |
| SCHEMBL8089993 | 0.75 | ACE (0.46) | CCKARCCKBR | |
| SCHEMBL7550570 | 0.74 | CCKAR (0.67) | CCKARCCKBR | |
| SCHEMBL7752992 | 0.72 | CCKAR (0.65) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694039-B1 | 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC AND OR AGONISTIC ACTIVITY | GLAXO WELLCOME INC (US) | 2001-01-24 | — | — | EP | disclosed |
| US-5646140-A | CHOLECYSTOKININ ANTAGONIST; APETITE CONTROL | GLAXO WELLCOME INC. (US) | 1997-07-08 | — | — | US | disclosed |