Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776464 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2GAARAB9APOLBALDH1A1 | |
| SCHEMBL776594 | 0.83 | KCNJ11 (0.63) | GAARAB9AKCNJ11ALDH1A1HPGD | |
| SCHEMBL7114320 | 0.80 | KCNJ11 (0.78) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL775262 | 0.78 | EP300 (0.61) | SMN1; SMN2GAARAB9AKCNJ11ALDH1A1 | |
| SCHEMBL776816 | 0.77 | EP300 (0.64) | SMN1; SMN2GAARAB9AKCNJ11ALDH1A1 | |
| SCHEMBL778783 | 0.77 | EP300 (0.64) | SMN1; SMN2GAARAB9AKCNJ11ALDH1A1 | |
| SCHEMBL12284941 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2GAARAB9APOLBALDH1A1 | |
| SCHEMBL675647 | 0.74 | ALDH1A1 (0.63) | GAARAB9APOLBALDH1A1HPGD | |
| SCHEMBL11116162 | 0.74 | CYP1A2 (0.46) | GAARAB9AKCNJ11ALDH1A1HPGD | |
| SCHEMBL9665541 | 0.73 | KMT2A (0.50) | SMN1; SMN2GAARAB9AKCNJ11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |