Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775301 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AGAAPOLBADORA1 | |
| SCHEMBL778848 | 0.84 | MAPK1 (0.51) | SMN1; SMN2RAB9AGAAPOLBADORA1 | |
| SCHEMBL776746 | 0.80 | LMNA (0.60) | SMN1; SMN2RAB9AGAAPOLBHPGD | |
| SCHEMBL776355 | 0.79 | NPC1 (0.59) | SMN1; SMN2RAB9AGAAPOLBHPGD | |
| SCHEMBL774893 | 0.79 | NPC1 (0.59) | SMN1; SMN2RAB9AGAAPOLBHPGD | |
| SCHEMBL5907677 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AGAAPOLBLMNA | |
| SCHEMBL31643225 | 0.75 | RAB9A (1.00) | SMN1; SMN2RAB9AGAAPOLBHPGD | |
| SCHEMBL4092873 | 0.74 | PTPN1 (0.59) | SMN1; SMN2RAB9AGAAPOLBADORA1 | |
| SCHEMBL777051 | 0.72 | NPC1 (0.54) | SMN1; SMN2RAB9APOLBADORA3HPGD | |
| SCHEMBL11658696 | 0.71 | RAB9A (0.41) | SMN1; SMN2RAB9AGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |