SCHEMBL7753316

SCHEMBL7753316

C=CC(=O)OC(F)(F)C(F)(F)OC(F)(F)C(F)CC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HPGD P15428 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9304290 0.85 TSHR (0.37) TSHRHPGDTHRB
SCHEMBL30294119 0.77 ALDH1A1 (0.34) TSHRHPGD
SCHEMBL19995641 0.77 TSHR (0.32) TSHRHPGD
SCHEMBL21819966 0.75 ALDH1A1 (0.38) TSHRHPGDTHRB
SCHEMBL786659 0.74 ALDH1A1 (0.32) TSHR
SCHEMBL4463492 0.73 TSHR (0.32) TSHR
SCHEMBL9301632 0.73 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL9312011 0.73 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL30951241 0.72 ALDH1A1 (0.31) TSHR
SCHEMBL786428 0.72 ALDH1A1 (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070173-A1 AQUEOUS BASED IMAGE RECEPTIVE COATING AND PROCESS FOR PRODUCING SAME A*Ware Technologies, L.C. (US) 2001-01-24 EP disclosed
WO-1999053138-A1 AQUEOUS BASED IMAGE RECEPTIVE COATING AND PROCESS FOR PRODUCING SAME A*WARE TECHNOLOGIES, L.C. (US) 1999-10-21 WO disclosed