Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.46 |
| ▸ | CHRNG | P07510 | 3/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.46 |
| ▸ | CHRND | Q07001 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898098 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1GRIA1CHRNA1 | |
| SCHEMBL6891324 | 0.95 | TACR2 (0.44) | MMP8KIFC1 | |
| SCHEMBL6897026 | 0.93 | L3MBTL1 (0.48) | MMP8MMP2MMP9KIFC1 | |
| SCHEMBL27538326 | 0.91 | MMP8 (0.42) | OPRM1OPRD1OPRK1GRIA1MMP8 | |
| SCHEMBL6890087 | 0.91 | AVPR1A (0.52) | OPRM1OPRD1OPRK1MMP8KIFC1 | |
| SCHEMBL6891355 | 0.91 | KIFC1 (0.45) | OPRM1OPRD1OPRK1MMP8KIFC1 | |
| SCHEMBL6898089 | 0.91 | MMP8 (0.42) | OPRM1OPRD1OPRK1GRIA1MMP8 | |
| SCHEMBL27538358 | 0.91 | AVPR1A (0.52) | OPRM1OPRD1OPRK1MMP8KIFC1 | |
| SCHEMBL6897535 | 0.90 | KMT2A (0.51) | OPRM1OPRD1MMP9CTSLKIFC1 | |
| SCHEMBL6898000 | 0.89 | MEN1 (0.43) | MMP8CTSLKIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |