Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.79 |
| ▸ | EBP | Q15125 | 4/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16910242 | 0.94 | SIGMAR1 (0.69) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| SCHEMBL4310502 | 0.89 | EBP (0.81) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| Triparanol SCHEMBL133384 | 0.88 | EBP (1.00) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| SCHEMBL330094 | 0.87 | SIGMAR1 (0.67) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| SCHEMBL10356744 | 0.82 | CYP2D6 (0.58) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| Triparanol SCHEMBL5488333 | 0.82 | EBP (0.86) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| SCHEMBL27944824 | 0.80 | CYP2D6 (0.56) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| SCHEMBL11684281 | 0.79 | CYP1A2 (0.66) | CYP2D6HTTCYP1A2CYP2C9LTA4H | |
| SCHEMBL8707174 | 0.78 | EBP (0.56) | SIGMAR1EBPCYP2D6HTTCYP1A2 | |
| SCHEMBL3420518 | 0.78 | EBP (0.64) | SIGMAR1EBPCYP2D6HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073752-A1 | PROTEIN WITH THE AMINO ACID SEQUENCE OF DELTA 7 STEROL REDUCTASE,ISOLATED cDNA MOLECULE CODING FOR SAID PROTEIN, RECOMBINANT DNA VECTOR AND BIOLOGICALLY ACTIVECOMPOSITIONS CONTAINING SAID PROTEIN OR SAID cDNA MOLECULE | Glossmann, Hartmut (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999013086-A1 | PROTEIN WITH THE AMINO ACID SEQUENCE OF Δ7 STEROL REDUCTASE, ISOLATED cDNA MOLECULE CODING FOR SAID PROTEIN, RECOMBINANT DNA VECTOR AND BIOLOGICALLY ACTIVE COMPOSITIONS CONTAINING SAID PROTEIN OR SAID cDNA MOLECULE | GLOSSMANN HARTMUT (DE) | 1999-03-18 | — | — | WO | disclosed |