Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.34 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902258 | 0.91 | ACHE (0.46) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| Sulfuric Acid SCHEMBL775349 | 0.90 | ACHE (0.39) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| Hydrochloric Acid SCHEMBL422093 | 0.89 | ACHE (0.44) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| Hydrochloric Acid SCHEMBL28681425 | 0.87 | ACHE (0.43) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| SCHEMBL18690258 | 0.83 | POLB (0.38) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| SCHEMBL2142810 | 0.80 | ACHE (0.56) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| Hydrochloric Acid SCHEMBL5605775 | 0.78 | ACHE (0.54) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| Ammonia Solution, Strong SCHEMBL28288492 | 0.77 | ACHE (0.52) | ACHEALDH1A1TSHRBBOX1ADRA2A | |
| SCHEMBL902256 | 0.76 | ALDH1A1 (0.44) | ACHEALDH1A1TSHRBBOX1 | |
| SCHEMBL30760187 | 0.74 | BBOX1 (0.40) | ALDH1A1TSHRBBOX1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331593-B1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | SOLENIS TECHNOLOGIES CAYMAN LP (CH) | 2016-02-24 | — | — | EP | claimed |
| US-9034146-B2 | Copolymer blend compositions for use to increase paper filler content | SOLENIS TECHNOLOGIES, L.P. (CH) | 2015-05-19 | — | — | US | claimed |
| US-8518216-B2 | Copolymer blend compositions for use to increase paper filler content | HERCULES INCORPORATED (US) | 2013-08-27 | — | — | US | claimed |
| US-20120071608-A1 | Copolymer Blend Compositions for Use to Increase Paper Filler Content | HERCULES INCORPORATED | 2012-03-22 | — | — | US | claimed |
| EP-2331593-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | Hercules Incorporated (US) | 2011-06-15 | — | — | EP | claimed |
| US-20100071863-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | US | claimed |
| WO-2010033796-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | WO | claimed |
| EP-2331593-B1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | SOLENIS TECHNOLOGIES CAYMAN LP (CH) | 2016-02-24 | — | — | EP | disclosed |
| US-9034146-B2 | Copolymer blend compositions for use to increase paper filler content | SOLENIS TECHNOLOGIES, L.P. (CH) | 2015-05-19 | — | — | US | disclosed |
| US-20140318728-A1 | Copolymer Blend Compositions For Use To Increase Paper Filler Content | HERCULES INCORPORATED (US) | 2014-10-30 | — | — | US | disclosed |
| US-8518216-B2 | Copolymer blend compositions for use to increase paper filler content | HERCULES INCORPORATED (US) | 2013-08-27 | — | — | US | disclosed |
| US-8163134-B2 | Copolymer blend compositions for use to increase paper filler content | HERCULES INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |
| US-20120071608-A1 | Copolymer Blend Compositions for Use to Increase Paper Filler Content | HERCULES INCORPORATED | 2012-03-22 | — | — | US | disclosed |
| EP-2331593-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | Hercules Incorporated (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20100071863-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | US | disclosed |
| WO-2010033796-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | WO | disclosed |