Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458578 | 0.80 | DRD2 (0.35) | DRD2SLC6A4 | |
| SCHEMBL9013264 | 0.78 | DRD2 (0.31) | DRD2SLC6A4 | |
| SCHEMBL11270086 | 0.73 | HDAC4 (0.37) | EPHX2ACMSDKMOSLC6A4 | |
| SCHEMBL27748636 | 0.73 | PRMT5 (0.33) | — | |
| SCHEMBL29026546 | 0.73 | ESR2 (0.36) | DRD2ACMSDKMO | |
| SCHEMBL6568489 | 0.72 | KMO (0.39) | EPHX2ACMSDKMO | |
| SCHEMBL29125236 | 0.72 | KMO (0.39) | EPHX2ACMSDKMO | |
| SCHEMBL28299092 | 0.71 | HDAC8 (0.38) | EPHX2ACMSDKMOSLC6A4 | |
| SCHEMBL16953245 | 0.70 | SPHK1 (0.38) | DRD2SLC6A4 | |
| SCHEMBL1778645 | 0.69 | KMO (0.40) | EPHX2ACMSDKMOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071660-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE | Novartis AG (CH) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999043644-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ | NOVARTIS AG (CH) | 1999-09-02 | — | — | WO | disclosed |