SCHEMBL7754150

SCHEMBL7754150

C=CC(=O)NCc1ccc(S(=O)(=O)NCC(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
TGM2 P21980 1/20 0.51
HSD17B10 Q99714 2/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 2/20 0.48
USP2 O75604 1/20 0.46
GAA P10253 2/20 0.44
HPGD P15428 1/20 0.44
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
PDK1 Q15118 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK3 Q15120 1/20 0.43
PDK4 Q16654 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754578 0.85 FBP1 (0.44) ALDH1A1TGM2HSD17B10MAPTLMNA
SCHEMBL393582 0.85 ALDH1A1 (0.57) ALDH1A1TGM2LMNAUSP2HPGD
SCHEMBL7754564 0.84 ALDH1A1 (0.56) ALDH1A1TGM2MAPTLMNAGAA
SCHEMBL398016 0.83 NAMPT (0.55) ALDH1A1TGM2MAPTLMNAUSP2
SCHEMBL394379 0.82 TGM2 (0.58) ALDH1A1TGM2MAPTUSP2GAA
SCHEMBL396211 0.82 MAPT (0.53) ALDH1A1TGM2MAPTLMNAGAA
SCHEMBL396729 0.81 LMNA (0.55) ALDH1A1TGM2LMNAUSP2MEN1
SCHEMBL7784363 0.78 ALDH1A1 (0.54) ALDH1A1TGM2MAPTLMNAUSP2
SCHEMBL398194 0.78 NAMPT (0.54) ALDH1A1TGM2MAPTLMNAUSP2
SCHEMBL395033 0.78 LMNA (0.66) ALDH1A1HSD17B10MAPTLMNAUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed