Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 9/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754452 | 0.90 | AR (0.33) | PDE2AARBCAT2BCAT1 | |
| SCHEMBL7753791 | 0.88 | AR (0.38) | ARBCAT2BCAT1LRRK2 | |
| SCHEMBL7749728 | 0.86 | BCAT2 (0.37) | ARBCAT2BCAT1CYP11B1CYP11B2 | |
| SCHEMBL7753787 | 0.83 | BCAT2 (0.35) | ARBCAT2BCAT1LRRK2 | |
| SCHEMBL7753846 | 0.82 | BRD4 (0.35) | PDE2AAR | |
| SCHEMBL7755922 | 0.79 | GLA (0.46) | ARBCAT2BCAT1KDM4EALDH1A1 | |
| SCHEMBL5841567 | 0.77 | RAB9A (0.42) | TRPV4BCAT2BCAT1KDM4EALDH1A1 | |
| SCHEMBL7754472 | 0.77 | BCL2A1 (0.31) | AR | |
| SCHEMBL8570147 | 0.77 | GAA (0.33) | GAA | |
| SCHEMBL7753821 | 0.76 | CYP11B1 (0.41) | TRPV4ARBCAT2BCAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |