Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 7/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 7/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749728 | 0.89 | BCAT2 (0.37) | ARBCAT2BCAT1 | |
| SCHEMBL7754759 | 0.88 | TRPV4 (0.35) | ARBCAT2BCAT1LRRK2 | |
| SCHEMBL7753787 | 0.87 | BCAT2 (0.35) | ARBCAT2BCAT1LRRK2EGFR | |
| SCHEMBL7754452 | 0.84 | AR (0.33) | ARBCAT2BCAT1PGR | |
| SCHEMBL4677779 | 0.83 | PPOX (0.43) | BCAT2BCAT1LRRK2 | |
| SCHEMBL7755922 | 0.83 | GLA (0.46) | ARBCAT2BCAT1 | |
| SCHEMBL7753846 | 0.78 | BRD4 (0.35) | ARPGR | |
| SCHEMBL4679803 | 0.75 | PPOX (0.44) | NR1I2 | |
| SCHEMBL4682459 | 0.75 | DHODH (0.34) | LRRK2 | |
| SCHEMBL31442437 | 0.75 | PPOX (0.44) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |