Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 7/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 7/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753791 | 0.87 | AR (0.38) | BCAT2BCAT1ARLRRK2EGFR | |
| SCHEMBL4248457 | 0.86 | PGK1 (0.35) | LRRK2 | |
| SCHEMBL7749728 | 0.85 | BCAT2 (0.37) | BCAT2BCAT1AR | |
| SCHEMBL7755922 | 0.84 | GLA (0.46) | BCAT2BCAT1AR | |
| SCHEMBL7754759 | 0.83 | TRPV4 (0.35) | BCAT2BCAT1ARLRRK2 | |
| SCHEMBL7754452 | 0.80 | AR (0.33) | BCAT2BCAT1AR | |
| SCHEMBL8063471 | 0.77 | PPOX (0.32) | — | |
| SCHEMBL7753846 | 0.76 | BRD4 (0.35) | AR | |
| SCHEMBL5843626 | 0.76 | BCAT2 (0.36) | BCAT2BCAT1 | |
| SCHEMBL6477318 | 0.74 | PGK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |