Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8859572 | 0.92 | CA2 (0.53) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL8758222 | 0.91 | LMNA (0.46) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL7754824 | 0.90 | LMNA (0.50) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL8757663 | 0.84 | CA2 (0.46) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL8859573 | 0.83 | LMNA (0.46) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL8758073 | 0.82 | LMNA (0.47) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL11522801 | 0.82 | ALDH1A1 (0.50) | CA2LMNAALDH1A1FFAR1GPR84 | |
| SCHEMBL3717342 | 0.82 | LMNA (0.45) | CA2LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL525160 | 0.80 | LMNA (0.62) | CA2LMNAALDH1A1GPR84TDP1 | |
| SCHEMBL7542521 | 0.80 | LMNA (0.62) | CA2LMNAALDH1A1GPR84TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |