Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1158253 | 0.89 | CHRM2 (0.45) | CHRM2CHRM1PPARDPPARAADRB2 | |
| Hydrochloric Acid SCHEMBL16166428 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1PPARDPPARAADRB2 | |
| SCHEMBL4661559 | 0.86 | ALOX15 (0.41) | CHRM2CHRM1PPARDPPARA | |
| SCHEMBL4659041 | 0.86 | CHRM2 (0.39) | ELANECHRM2CHRM1CYP3A4 | |
| SCHEMBL11297469 | 0.86 | CHRM2 (0.35) | CHRM2CHRM1PPARDPPARAADRB2 | |
| SCHEMBL4660261 | 0.85 | MTNR1B (0.40) | CHRM2CHRM1 | |
| SCHEMBL7758293 | 0.85 | ELANE (0.38) | ELANECHRM2CHRM1PPARDPPARA | |
| SCHEMBL4660356 | 0.84 | ESR1 (0.35) | ELANECHRM2CHRM1ADRB2 | |
| SCHEMBL4660393 | 0.83 | MEN1 (0.36) | CHRM2CHRM1CYP3A4ADRB2 | |
| SCHEMBL4659042 | 0.83 | MAPT (0.35) | ELANECHRM2CHRM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |