Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222348 | 0.88 | TDP1 (0.49) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL1222350 | 0.88 | TDP1 (0.49) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL3166361 | 0.88 | TDP1 (0.49) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL10490841 | 0.86 | MEN1 (0.40) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL24760710 | 0.85 | MEN1 (0.44) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL15069849 | 0.83 | MEN1 (0.42) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL13857951 | 0.80 | APLNR (0.45) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL570033 | 0.79 | MEN1 (0.50) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL19812412 | 0.78 | CTSK (0.41) | CTSSCTSKCA1CA2CA7 | |
| SCHEMBL18756327 | 0.77 | APLNR (0.43) | TDP1MEN1KMT2AGAAAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797110-B1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO KG (DE) | 2011-01-12 | — | — | EP | disclosed |
| EP-0835238-B1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-21 | — | — | EP | disclosed |
| US-6060455-A | AGGREGATION WITH RNA OR DNA; DELIVERY INTO CELLS | BOEHRINGER MANNHEIM GMBH (DE) | 2000-05-09 | — | — | US | disclosed |
| EP-0835238-A1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | Roche Diagnostics GmbH (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997000241-A1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-03 | — | — | WO | disclosed |