Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161223 | 0.71 | NOS3 (0.51) | NOS3NOS1NOS2 | |
| SCHEMBL7571471 | 0.69 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL623332 | 0.69 | — | — | |
| SCHEMBL2161551 | 0.68 | NOS3 (0.57) | NOS3NOS1NOS2 | |
| SCHEMBL11188012 | 0.66 | NOS3 (0.62) | NOS3NOS1NOS2 | |
| SCHEMBL6727321 | 0.64 | GRIN2D (0.47) | NOS3NOS1NOS2 | |
| SCHEMBL7277974 | 0.64 | NOS3 (0.60) | NOS3NOS1NOS2 | |
| Nitric Acid SCHEMBL332649 | 0.64 | CA5A (0.47) | NOS3NOS1NOS2 | |
| SCHEMBL2519792 | 0.64 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| Nitric Acid SCHEMBL7461340 | 0.64 | CA5A (0.47) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1309703-A | Mutants of mycobacterium species and use of same for screening for antibiotics vectors | GRUELENTHAL GMBH (DE) | 2001-08-22 | — | — | CN | disclosed |
| WO-1999054454-A9 | MUTANTS OF THE MYCOBACTERIUM SPECIES AND USE OF THE SAME FOR SCREENING FOR ANTIBIOTICS VECTORS | GRUENENTHAL GMBH (DE) | 2001-03-15 | — | — | WO | disclosed |
| EP-1071761-A1 | MUTANTS OF THE MYCOBACTERIUM SPECIES AND USE OF THE SAME FOR SCREENING FOR ANTIBIOTICS VECTORS | Grünenthal GmbH (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054454-A1 | MUTANTS OF THE MYCOBACTERIUM SPECIES AND USE OF THE SAME FOR SCREENING FOR ANTIBIOTICS VECTORS | Grünenthal GmbH (DE) | 1999-10-28 | — | — | WO | disclosed |