Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771740 | 0.77 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL28729197 | 0.70 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL7755601 | 0.69 | NOS3 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL2161223 | 0.69 | NOS3 (0.51) | NOS3NOS1NOS2GRIN2DGRIN3B | |
| SCHEMBL6026437 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL9242372 | 0.67 | — | — | |
| SCHEMBL1449843 | 0.67 | — | — | |
| SCHEMBL2161551 | 0.67 | NOS3 (0.57) | NOS3NOS1NOS2GRIN2DGRIN3B | |
| SCHEMBL9424082 | 0.66 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14719770 | 0.66 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220118004-A1 | TUNABLE IMMUNE RESPONSIVE BIODEGRADABLE ARGININE-BASED POLY(ESTER AMIDE)S AND METHODS OF MAKING AND USING SAME | UNIV CORNELL (US) | 2022-04-21 | — | — | US | claimed |
| CN-101565392-A | Methyl nitroguanidine and preparation method thereof | NANTONG TENDENCI CHEMICAL CO L (CN) | 2009-10-28 | — | — | CN | claimed |
| US-20220118004-A1 | TUNABLE IMMUNE RESPONSIVE BIODEGRADABLE ARGININE-BASED POLY(ESTER AMIDE)S AND METHODS OF MAKING AND USING SAME | UNIV CORNELL (US) | 2022-04-21 | — | — | US | disclosed |
| CN-102344394-B | Preparation method of nitroguanidine and its derivatives N-methylnitroguanidine and oxadiazine | HEBEI KEEPER CHEMICAL IND CO LTD | 2012-11-28 | — | — | CN | disclosed |
| CN-1826429-B | Method and solution for coating metal surfaces with a phosphating solution containing water peroxide, produced metal object and use of said object | CHEMETALL GMBH | 2012-08-08 | — | — | CN | disclosed |
| CN-102344394-A | Preparation method of nitroguanidine and its derivatives N-methylnitroguanidine and oxadiazine | HEBEI KEEPER CHEMICAL IND CO LTD | 2012-02-08 | — | — | CN | disclosed |
| CN-101565392-A | Methyl nitroguanidine and preparation method thereof | NANTONG TENDENCI CHEMICAL CO L (CN) | 2009-10-28 | — | — | CN | disclosed |
| CN-101565392-A | Methyl nitroguanidine and preparation method thereof | NANTONG TENDENCI CHEMICAL CO L (CN) | 2009-10-28 | — | — | CN | disclosed |
| CN-1826429-A | Method and solution for coating metal surfaces with a phosphating solution containing water peroxide, produced metal object and use of said object | CHEMETALL GMBH (DE) | 2006-08-30 | — | — | CN | disclosed |
| EP-1218362-A1 | METHOD FOR PRODUCING 3-ALKYL-N-NITRO-4H-1,3,5-OXADIAZINE-4-IMINES | NIGU CHEMIE GMBH (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025222-A1 | METHOD FOR PRODUCING 3-ALKYL-N-NITRO-4H-1,3,5-OXADIAZINE-4-IMINES | NIGU CHEMIE GMBH (DE) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118004-A1 | TUNABLE IMMUNE RESPONSIVE BIODEGRADABLE ARGININE-BASED POLY(ESTER AMIDE)S AND METHODS OF MAKING AND USING SAME | ARG1, LRBA, ARG2 | NOS3 8/4885NOS1 12/4885NOS2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.