Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.60 |
| ▸ | NOS1 | P29475 | 1/20 | 0.60 |
| ▸ | NOS2 | P35228 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431660 | 0.98 | NOS3 (0.59) | NOS3NOS1NOS2LMNANFKB1 | |
| SCHEMBL11188012 | 0.95 | NOS3 (0.62) | NOS3NOS1NOS2LMNANFKB1 | |
| SCHEMBL2161551 | 0.77 | NOS3 (0.57) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL5271958 | 0.76 | NOS1 (1.00) | NOS3NOS1NOS2NFKB1TSHR | |
| SCHEMBL9772203 | 0.73 | NOS3 (0.57) | NOS3NOS1NOS2 | |
| Acetic Acid SCHEMBL29403856 | 0.72 | NOS2 (0.91) | NOS3NOS1NOS2NFKB1TSHR | |
| SCHEMBL9442579 | 0.72 | TSHR (0.50) | LMNANFKB1TSHRPMP22CYP2D6 | |
| SCHEMBL2161223 | 0.72 | NOS3 (0.51) | NOS3NOS1NOS2TSHRCYP2D6 | |
| SCHEMBL28455132 | 0.72 | LMNA (0.46) | LMNANFKB1TSHRPMP22CYP2D6 | |
| SCHEMBL3670340 | 0.71 | NOS3 (0.51) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |