Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 3/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948314 | 0.82 | AKR1B1 (0.55) | AKR1B1BCAT2TDP1CXCL8LMNA | |
| SCHEMBL8746636 | 0.81 | AKR1B1 (0.46) | AKR1B1CTBP2BCAT2TDP1USP2 | |
| SCHEMBL11467086 | 0.76 | AKR1B1 (0.42) | AKR1B1CTBP2TDP1USP2ALDH1A1 | |
| SCHEMBL7336703 | 0.74 | AKR1B1 (0.41) | AKR1B1CTBP2TDP1ALDH1A1MAPT | |
| SCHEMBL1137307 | 0.74 | AKR1B1 (0.67) | AKR1B1TDP1 | |
| SCHEMBL1627494 | 0.73 | CTBP2 (0.59) | AKR1B1CTBP2CXCL8ALDH1A1MAPT | |
| SCHEMBL7441996 | 0.73 | CTBP2 (0.59) | CTBP2ALDH1A1MAPTHTT | |
| SCHEMBL9310058 | 0.73 | ALDH1A1 (0.42) | AKR1B1CTBP2ALDH1A1LMNA | |
| SCHEMBL6471673 | 0.73 | CYP1A2 (0.54) | AKR1B1CTBP2TDP1USP2ALDH1A1 | |
| SCHEMBL11391048 | 0.73 | FDPS (0.40) | AKR1B1CTBP2TDP1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070752-A1 | PROCESS FOR THE PREPARATION OF 2-CARBOXY-ALKYL(ARYL)PHOSPHONIC ACIDS AND ANHYDRIDE(S) | SOLUTIA INC. (US) | 2001-09-27 | — | — | WO | claimed |