Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759387 | 0.90 | NPC1 (0.47) | SMN1; SMN2HPGDRAB9AALDH1A1POLB | |
| SCHEMBL7761165 | 0.89 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2AFAAHMGLL | |
| SCHEMBL7756146 | 0.83 | NPC1 (0.49) | SMN1; SMN2MEN1KMT2AHPGDRAB9A | |
| SCHEMBL1972122 | 0.81 | BCL9 (0.51) | SMN1; SMN2MEN1KMT2AMGLLBCL9 | |
| SCHEMBL7759913 | 0.78 | ELANE (0.45) | SMN1; SMN2MEN1KMT2AHPGDRAB9A | |
| SCHEMBL8816649 | 0.75 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AMGLLKDM4EBCL9 | |
| SCHEMBL395369 | 0.75 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AKDM4ERAB9ABCL9 | |
| SCHEMBL278663 | 0.75 | BCL9 (0.62) | SMN1; SMN2MEN1KMT2AMGLLHPGD | |
| SCHEMBL9485717 | 0.73 | HSPB1 (0.53) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL1118843 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AMGLLKDM4EBCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092712-A1 | Process for preparing fungicidal oxazolidinones and imidazolinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |