Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MYOC | Q99972 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759913 | 0.89 | ELANE (0.45) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7756209 | 0.89 | SMN1; SMN2 (0.44) | ALDH1A1POLBFAAHKDM4EFFAR1 | |
| SCHEMBL7760774 | 0.82 | KCNN4 (0.50) | ALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL7759387 | 0.77 | NPC1 (0.47) | ALDH1A1POLBSMN1; SMN2MAPTNPC1 | |
| SCHEMBL8816649 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2MGLLKMT2A | |
| SCHEMBL9485717 | 0.75 | HSPB1 (0.53) | ALDH1A1KDM4EFFAR1SMN1; SMN2MEN1 | |
| SCHEMBL1118843 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2MGLLKMT2A | |
| SCHEMBL20377184 | 0.75 | SMN1; SMN2 (0.64) | ALDH1A1POLBFAAHKDM4ESMN1; SMN2 | |
| SCHEMBL6322393 | 0.75 | SMN1; SMN2 (0.64) | ALDH1A1POLBFAAHKDM4ESMN1; SMN2 | |
| SCHEMBL1461897 | 0.73 | ELANE (0.60) | ALDH1A1SMN1; SMN2MGLLKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092712-A1 | Process for preparing fungicidal oxazolidinones and imidazolinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |