Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760774 | 0.91 | KCNN4 (0.50) | ELANEL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL7761165 | 0.89 | ALDH1A1 (0.45) | SMN1; SMN2MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL7759387 | 0.86 | NPC1 (0.47) | ELANEHPGDSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3191632 | 0.81 | SMN1; SMN2 (0.51) | ELANEHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7756209 | 0.78 | SMN1; SMN2 (0.44) | HPGDSMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL7756146 | 0.78 | NPC1 (0.49) | HPGDSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL545687 | 0.77 | HPGD (0.58) | HPGDSMN1; SMN2PGRRAB9ANPC1 | |
| SCHEMBL19846658 | 0.76 | TDP1 (0.49) | ELANEHPGDSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL7759944 | 0.76 | SMN1; SMN2 (0.50) | ELANEHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL13924997 | 0.75 | L3MBTL1 (0.54) | ELANESMN1; SMN2L3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092712-A1 | Process for preparing fungicidal oxazolidinones and imidazolinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |