Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756751 | 0.99 | SIGMAR1 (0.44) | DRD2SLC6A4SLC6A3LTA4HSIGMAR1 | |
| SCHEMBL7759822 | 0.89 | SIGMAR1 (0.48) | DRD2SIGMAR1KCNJ1 | |
| SCHEMBL9449426 | 0.82 | SIGMAR1 (0.57) | DRD2SIGMAR1 | |
| SCHEMBL8958333 | 0.80 | SIGMAR1 (0.58) | DRD2SIGMAR1 | |
| SCHEMBL7761410 | 0.80 | DRD2 (0.61) | DRD2 | |
| SCHEMBL8785466 | 0.77 | DRD2 (0.46) | DRD2SLC6A4 | |
| SCHEMBL8787068 | 0.77 | HTR1A (0.58) | DRD2 | |
| SCHEMBL8785483 | 0.76 | HTR1A (0.48) | DRD2SLC6A4SLC6A3SIGMAR1HRH1 | |
| SCHEMBL9684693 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL8116069 | 0.74 | CCR3 (0.57) | SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |