Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731669 | 0.83 | ALDH1A1 (0.57) | PLA2G1BATG4BSGMS2LMNAALDH1A1 | |
| SCHEMBL21437008 | 0.83 | PLA2G1B (0.57) | PLA2G1BATG4BSGMS2LMNAALDH1A1 | |
| SCHEMBL21439851 | 0.82 | POLB (0.60) | PLA2G1BATG4BLMNAALDH1A1POLB | |
| SCHEMBL3365176 | 0.81 | CTSD (0.68) | ALDH1A1SMN1; SMN2HPGDMAPK1POLB | |
| SCHEMBL7756903 | 0.81 | BRD4 (0.53) | ALDH1A1SMN1; SMN2MAPK1MAPTPOLB | |
| SCHEMBL21455860 | 0.81 | BRD4 (0.48) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL29359562 | 0.81 | BRD4 (0.48) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL30849274 | 0.80 | PARP1 (0.71) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| Hydrochloric Acid SCHEMBL9585041 | 0.80 | CTSD (0.66) | ALDH1A1SMN1; SMN2HPGDMAPK1POLB | |
| SCHEMBL3074897 | 0.79 | SPHK2 (0.65) | SGMS2LMNAALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |