Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760034 | 0.87 | MAPT (0.51) | MAPTHDAC3NCOR1HDAC1HDAC2 | |
| SCHEMBL7761944 | 0.82 | KMT2A (0.67) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7761717 | 0.81 | KDM4E (0.62) | MAPTHDAC3NCOR1HDAC1HDAC2 | |
| SCHEMBL7756878 | 0.80 | KDM4E (0.58) | HDAC3HDAC1HDAC2KMT2AMEN1 | |
| SCHEMBL7756903 | 0.78 | BRD4 (0.53) | MAPTHDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL7300289 | 0.78 | MAPT (0.62) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8495430 | 0.75 | MAPT (0.50) | MAPTHDAC3NCOR1HDAC1HDAC2 | |
| SCHEMBL7760048 | 0.73 | MAPT (0.50) | MAPTHDAC3NCOR1HDAC1HDAC2 | |
| SCHEMBL13366908 | 0.72 | CASR (0.63) | HDAC1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8837485 | 0.72 | MAPT (0.44) | MAPTHDAC3NCOR1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |