SCHEMBL7757112

SCHEMBL7757112

O=C(OCCCc1cccnc1)[C@@H]1CCCN1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 12/20 0.54
MTOR P42345 1/20 0.51
FKBP4 Q02790 1/20 0.51
FKBP5 Q13451 1/20 0.51
CHRNA7 P36544 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6926542 1.00 FKBP1A (0.54) FKBP1AMTORFKBP4FKBP5CHRNA7
SCHEMBL21241510 0.85 LMNA (0.50) FKBP1A
SCHEMBL22861524 0.85 LMNA (0.50) FKBP1A
SCHEMBL22861529 0.82 FKBP1A (0.50) FKBP1A
SCHEMBL25756614 0.82 FKBP1A (0.50) FKBP1A
SCHEMBL11181788 0.82 FKBP1A (0.67) FKBP1AMTORFKBP4FKBP5CHRNA7
SCHEMBL11178538 0.82 FKBP1A (0.64) FKBP1AMTORFKBP4FKBP5CHRNA7
SCHEMBL11658981 0.81 FKBP1A (0.60) FKBP1AMTORFKBP4FKBP5CHRNA7
SCHEMBL20601954 0.81 FKBP1A (0.55) FKBP1AMTORFKBP4FKBP5CHRNA7
SCHEMBL16586222 0.80 FKBP1A (0.52) FKBP1AFKBP4FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083875-A1 SMALL MOLECULE CARBAMATE OR UREA HAIR GROWTH COMPOSITIONS AND USES GPI NIL Holdings, Inc. (US) 2001-03-21 EP disclosed
WO-1999062484-A1 SMALL MOLECULE CARBAMATE OR UREA HAIR GROWTH COMPOSITIONS AND USES GPI NIL HOLDINGS, INC. (US) 1999-12-09 WO disclosed