Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 12/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.51 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757112 | 1.00 | FKBP1A (0.54) | FKBP1AMTORFKBP4FKBP5CHRNA7 | |
| SCHEMBL21241510 | 0.85 | LMNA (0.50) | FKBP1A | |
| SCHEMBL22861524 | 0.85 | LMNA (0.50) | FKBP1A | |
| SCHEMBL22861529 | 0.82 | FKBP1A (0.50) | FKBP1A | |
| SCHEMBL25756614 | 0.82 | FKBP1A (0.50) | FKBP1A | |
| SCHEMBL11181788 | 0.82 | FKBP1A (0.67) | FKBP1AMTORFKBP4FKBP5CHRNA7 | |
| SCHEMBL11178538 | 0.82 | FKBP1A (0.64) | FKBP1AMTORFKBP4FKBP5CHRNA7 | |
| SCHEMBL11658981 | 0.81 | FKBP1A (0.60) | FKBP1AMTORFKBP4FKBP5CHRNA7 | |
| SCHEMBL20601954 | 0.81 | FKBP1A (0.55) | FKBP1AMTORFKBP4FKBP5CHRNA7 | |
| SCHEMBL16586222 | 0.80 | FKBP1A (0.52) | FKBP1AFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114492-A1 | Method of using neurotrophic sulfonamide compounds | HAMILTON GREGORY S (US) | 2003-06-19 | — | — | US | disclosed |
| EP-1014978-A4 | METHOD OF USING NEUTROPHIC SULFONAMIDE COMPOUNDS | GUILFORD PHARM INC (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6395758-B1 | VISION DEFECTS | GPI NIL HOLDINGS, INC. | 2002-05-28 | — | — | US | disclosed |
| US-20020037924-A1 | Small molecule carbamate or urea hair growth compositions and uses | GPI NIL HOLDINGS, INC. (US) | 2002-03-28 | — | — | US | disclosed |
| US-6333340-B1 | SULFONAMIDES WITH OXO, ESTER OR AMIDE GROUPS FOR VISION DEFECTS AND COGNITION ACTIVATORS | GPI NIL HOLDINGS, INC. | 2001-12-25 | — | — | US | disclosed |
| US-20010029261-A1 | Small molecule sulfonamide hair growth compositions and uses | GUILFORD PHARMACEUTICALS INC. | 2001-10-11 | — | — | US | disclosed |
| EP-1107757-A2 | CARBAMATE AND UREA COMPOSITIONS AND NEUROTROPHIC USES | GUILFORD PHARMACEUTICALS INC. (US) | 2001-06-20 | — | — | EP | disclosed |
| EP-1105131-A2 | SMALL MOLECULE CARBAMATES OR UREAS FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1105125-A2 | USE OF SULFONAMIDES FOR TREATING VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6245783-B1 | NERVOUS SYSTEM DISORDERS | GPI NIL HOLDINGS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6187796-B1 | ALOPECIA TREATMENT; IMMUNOPHILIN AFFINITY | GPI NIL HOLDINGS, INC. | 2001-02-13 | — | — | US | disclosed |
| EP-1014978-A1 | METHOD OF USING NEUTROPHIC SULFONAMIDE COMPOUNDS | GPI NIL Holdings, Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000010553-A2 | CARBAMATE AND UREA COMPOSITIONS AND NEUROTROPHIC USES | GPI NIL HOLDINGS, INC. (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-2000009104-A2 | USE OF SULFONAMIDES FOR TREATING VISION AND MEMORY DISORDERS | GPI NHL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000009105-A2 | SMALL MOLECULE CARBAMATES OR UREAS FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-1999062490-A1 | SMALL MOLECULE SULFONAMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1999062484-A1 | SMALL MOLECULE CARBAMATE OR UREA HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| US-5968957-A | ADMINISTERING TO EFFECT NEURONAL ACTIVITY | GPI NIL HOLDINGS, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1998035675-A1 | METHOD OF USING NEUROTROPHIC SULFONAMIDE COMPOUNDS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-08-20 | — | — | WO | disclosed |
| US-5721256-A | INHIBITORS OF THE ENZYME ACTIVITY ASSOCIATED WITH IMMUNOPHILIN PROTEINS | GPI NIL HOLDINGS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114492-A1 | Method of using neurotrophic sulfonamide compounds | PRSS12, FKBP8, FKBP14 | FKBP1A 5/4885MTOR 1360/4885FKBP4 10/4885 |
| US-20020037924-A1 | Small molecule carbamate or urea hair growth compositions and uses | SHH, CPS1, SLC14A1 | FKBP1A 1457/4885MTOR 88/4885FKBP4 2137/4885 |
| US-20010029261-A1 | Small molecule sulfonamide hair growth compositions and uses | PSAP, SHH, SPTSSB | FKBP1A 152/4885MTOR 87/4885FKBP4 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.