SCHEMBL7757536

SCHEMBL7757536

NC(=O)N(C(=O)c1c(Cl)cccc1Cl)c1ccc(Br)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RORC P51449 7/20 0.41
TLR7 Q9NYK1 1/20 0.35
KIF11 P52732 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
GAA P10253 4/20 0.34
LMNA P02545 1/20 0.34
PKM P14618 1/20 0.34
KMT2A Q03164 1/20 0.34
PBRM1 Q86U86 1/20 0.34
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28509729 0.88 RORC (0.36) RORCGAALMNAKMT2APBRM1
SCHEMBL7753768 0.88 RORC (0.42) RORCTLR7NR1H4GAAPBRM1
SCHEMBL7760787 0.88 RORC (0.45) RORCTLR7NR1H4GAAKMT2A
SCHEMBL28495673 0.88 RORC (0.36) RORCTLR7LMNAKMT2AITGB2
SCHEMBL7759310 0.84 RORC (0.40) RORCTLR7NR1H4GAALMNA
SCHEMBL7760781 0.82 RORC (0.43) RORCGAALMNAPKMKMT2A
SCHEMBL28500688 0.80 RORC (0.39) RORCTLR7LMNAKMT2AALDH1A1
SCHEMBL7759289 0.80 ALDH1A1 (0.39) RORCGAALMNAKMT2AALDH1A1
SCHEMBL7758920 0.80 RORC (0.45) RORCTLR7GAAKMT2APBRM1
SCHEMBL29034043 0.78 CYP3A4 (0.39) RORCGAALMNAPKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed