SCHEMBL7758920

SCHEMBL7758920

NC(=O)N(C(=O)c1c(F)cccc1F)c1ccc(Cl)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RORC P51449 10/20 0.45
TLR7 Q9NYK1 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
GAA P10253 3/20 0.36
PBRM1 Q86U86 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760787 0.91 RORC (0.45) RORCTLR7GAAPBRM1MEN1
SCHEMBL28504083 0.91 RORC (0.45) RORCTLR7TDP1CES2CES1
SCHEMBL11321971 0.84 GAA (0.41) RORCTDP1CES2CES1GAA
SCHEMBL7753768 0.83 RORC (0.42) RORCTLR7GAAPBRM1ITGB2
SCHEMBL28505329 0.80 CES2 (0.42) RORCTDP1CES2CES1GAA
SCHEMBL10719934 0.80 RORC (0.41) RORCTDP1CES2CES1GAA
SCHEMBL7757536 0.80 RORC (0.41) RORCTLR7GAAPBRM1KMT2A
SCHEMBL7759310 0.80 RORC (0.40) RORCTLR7GAAPBRM1KMT2A
SCHEMBL6699639 0.79 PTGIR (0.33) RORC
SCHEMBL28454874 0.79 ESR1 (0.47) RORCTDP1CES2CES1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed