SCHEMBL7760787

SCHEMBL7760787

NC(=O)N(C(=O)c1c(Cl)cccc1Cl)c1ccc(Cl)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RORC P51449 10/20 0.45
TLR7 Q9NYK1 1/20 0.37
GAA P10253 3/20 0.36
PBRM1 Q86U86 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753768 0.91 RORC (0.42) RORCTLR7GAAPBRM1NR1H4
SCHEMBL7758920 0.91 RORC (0.45) RORCTLR7GAAPBRM1MEN1
SCHEMBL7759310 0.88 RORC (0.40) RORCTLR7GAAPBRM1NR1H4
SCHEMBL7757536 0.88 RORC (0.41) RORCTLR7GAAPBRM1NR1H4
SCHEMBL28500688 0.87 RORC (0.39) RORCTLR7ALDH1A1MEN1KMT2A
SCHEMBL28504083 0.83 RORC (0.45) RORCTLR7GAAPBRM1ITGB2
SCHEMBL29034043 0.81 CYP3A4 (0.39) RORCGAAALDH1A1KMT2A
SCHEMBL29034050 0.81 ALDH1A1 (0.37) RORCTLR7NR1H4ALDH1A1MEN1
SCHEMBL28500692 0.80 ALDH1A1 (0.41) RORCGAAALDH1A1
SCHEMBL28509729 0.80 RORC (0.36) RORCGAAPBRM1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed