SCHEMBL7757646

SCHEMBL7757646

CCC1CCC(N=C=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 1/20 0.37
APLNR P35414 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25118389 0.94 ALDH1A1 (0.45) ALDH1A1CYP3A4APLNR
SCHEMBL1493007 0.83 ALDH1A1 (0.46) ALDH1A1CYP3A4APLNR
SCHEMBL8733246 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL6318341 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL10507329 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL23743495 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL5070945 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL5903114 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL7192102 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR
SCHEMBL22543 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114026496-A Photosensitive resin composition, photosensitive resin film, method for producing cured product, laminate, and electronic device 昭和电工材料株式会社 2022-02-08 CN disclosed
CN-107108782-B Terminal-modified soluble polyfunctional vinyl aromatic co-polymer and its application 日铁化学材料株式会社 2019-12-03 CN disclosed
EP-2809650-B1 ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE UNIV CALIFORNIA (US) 2018-04-11 EP disclosed
CN-107108782-A Terminal-modified soluble polyfunctional vinyl aromatic co-polymer, curable resin composition and use its light guide wave duct 新日铁住金化学株式会社 2017-08-29 CN disclosed
US-9034903-B2 Acyl piperidine inhibitors of soluble epoxide hydrolase THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-05-19 US disclosed
US-9034903-B2 Acyl piperidine inhibitors of soluble epoxide hydrolase THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-05-19 US disclosed
US-20150011586-A1 Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase THE REGENTS OF THE UNVERSITY OF CALIFORNIA 2015-01-08 US disclosed
US-20150011586-A1 Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase THE REGENTS OF THE UNVERSITY OF CALIFORNIA 2015-01-08 US disclosed
WO-2013116690-A1 ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-08-08 WO disclosed
WO-2001057106-A1 PHOTOCHROMIC COATED ARTICLES PPG INDUSTRIES OHIO, INC. (US) 2001-08-09 WO disclosed
US-5639892-A ANTIDEPRESSANTS, ALZHEIMER'S DISEASE HOECHST-MARION-ROUSSEL, INC. (US) 1997-06-17 US disclosed
US-5621114-A REACTING A THIO OR PHENOL COMPOUND WITH 1,1-CARBONYLIMIDAZOLE OR 1,1-THIOCARBONYLDIIMIDAZOLE, REACTING THE INTERMEDIATE WITH SECONDARY AMINE COMPOUND; USEFUL AS ANALGESIC AND MEMORY ENHANCING AGENT HOECHST MARION ROUSSEL, INC. (US) 1997-04-15 US disclosed
US-5550254-A REACTING CARBOXYLIC ACID WITH CARBONYLDIIMIDAZOLE OR THIOCARBONYLDIIMIDAZOLE, ADDING PHENOL OR THIOPHENOL COMPOUND HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-08-27 US disclosed
US-5550253-A REACTING PHENOL OR THIOPHENOL DERIVATIVE WITH LOWER ALKYL P-TOLUENESULFONATE, OPTIONALLY REDUCING NITRO GROUPS TO AMINO GROUPS AND ACYLATING OR ALKYLATING THEM HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-08-27 US disclosed
US-5547977-A Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8(and 1,3A,8)-di (and Tri) methylpyrrolo (2,3-B) indoles HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-08-20 US disclosed
US-5541340-A Method of preparing 1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-Di(and Tri)methylpyrrolo[2,3,-b] indoles HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-07-30 US disclosed
US-5541216-A Memory enhancing and analgsic 1,2,3,3A,8,8A-Hexahydro--3A, 8(And1,3A,8)-Di (and Tri) Methylpyrrolo(2,3-B Indoles HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-07-30 US disclosed
US-5187165-A Eseroline derivatives; cholinergic agents; antidepressants HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1993-02-16 US disclosed
US-4791107-A Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-12-13 US disclosed
EP-0253372-A2 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1988-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011586-A1 Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase EPHX1, FAAH, FAAH2 ALDH1A1 86/4885CYP3A4 320/4885APLNR 655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.