⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543780 | 0.85 | ALDH1A1 (0.44) | — | |
| SCHEMBL28426193 | 0.78 | — | — | |
| SCHEMBL777812 | 0.78 | ALDH1A1 (0.70) | — | |
| SCHEMBL777671 | 0.75 | ALDH1A1 (0.67) | — | |
| SCHEMBL776647 | 0.75 | ALDH1A1 (1.00) | — | |
| SCHEMBL14303351 | 0.74 | MAOA (0.44) | — | |
| SCHEMBL12110783 | 0.73 | ALDH1A1 (0.63) | — | |
| SCHEMBL9546524 | 0.72 | KMT2A (0.47) | — | |
| SCHEMBL14821022 | 0.72 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL2729285 | 0.72 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955349-A | Synthesis process of electrophilic fluoroalkylation reagent | 浙江瑞博制药有限公司 | 2024-11-15 | — | — | CN | claimed |
| EP-4720067-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | Recursion Pharmaceuticals, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12503438-B2 | Compounds for the treatment of kinase-dependent disorders | EXELIXIS, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| WO-2024246559-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | EXSCIENTIA AI LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |
| CN-118955349-A | Synthesis process of electrophilic fluoroalkylation reagent | 浙江瑞博制药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-114040912-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-10-25 | — | — | CN | disclosed |
| US-12100809-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| US-20240297344-A1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-05 | — | — | US | disclosed |
| WO-2024112759-A1 | NEGATIVE NMDA-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| CN-113493386-B | Novel high-selectivity asymmetric synthesis process of 2-fluorocyclopropylamine | 北京桦冠生物技术有限公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-1999018947-A1 | PROCESS TO MAKE CHIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| EP-0909754-A1 | Process to make chiral compounds | ELI LILLY AND COMPANY (US) | 1999-04-21 | — | — | EP | disclosed |
| EP-0905109-A1 | Fluorination with aminosulfur trifluorides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993023370-A1 | PROCESS FOR THE PREPARATION OF FLUOROMETHYL THIO BENZENES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| CN-1043499-A | The method for preparing the whole haloalkyl thioether | RHONE POULENC AGROCHIMIE (FR) | 1990-07-04 | — | — | CN | disclosed |
| EP-0147298-B1 | SULFONYLATION PROCESS | RHONE-POULENC CHIMIE (FR) | 1989-04-26 | — | — | EP | disclosed |
| EP-0147299-B1 | PROCESS FOR THE PREPARATION OF BENZOPHENONES | RHONE-POULENC CHIMIE (FR) | 1988-03-02 | — | — | EP | disclosed |
| US-4618726-A | DEACTIVATED BENZENE COMPOUND WITH CARBONYL HALIDE IN LIQUID HYDROFLUORIC ACID AND BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-10-21 | — | — | US | disclosed |
| EP-0147298-A2 | Sulfonylation process | RHONE-POULENC CHIMIE (FR) | 1985-07-03 | — | — | EP | disclosed |