SCHEMBL7757699

SCHEMBL7757699

SN1Cc2ccccc2O1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.39
MAOB P27338 3/20 0.39
TSHR P16473 1/20 0.35
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
OXTR P30559 1/20 0.33
HSD17B3 P37058 1/20 0.33
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP7 Q9UHL4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5530904 0.74 MAOA (0.41) MAOAMAOBTSHRALDH1A1GAA
SCHEMBL6645559 0.73 MAOA (0.39) MAOAMAOBTSHRALDH1A1GAA
SCHEMBL17185668 0.73 MAOA (0.39) MAOAMAOBTSHRGAAKMT2A
SCHEMBL6414082 0.68 MAOA (0.35) MAOAMAOBGAAKMT2ASMN1; SMN2
SCHEMBL8648635 0.67 HSD17B3 (0.36) TSHRALDH1A1KMT2ASMN1; SMN2MEN1
SCHEMBL14833074 0.66 HSD17B3 (0.38) MAOAMAOBTSHRALDH1A1GAA
SCHEMBL6199231 0.66 NISCH (0.38) MAOAMAOBALDH1A1GAAKMT2A
SCHEMBL7334246 0.66 CYP1A2 (0.45) MAOAMAOBTSHRKMT2AHSD17B3
SCHEMBL4884063 0.64 MAOA (0.44) MAOAMAOBTSHRALDH1A1GAA
SCHEMBL3074962 0.64 OXTR (0.42) MAOAMAOBTSHRGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626379-B1 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 2001-03-21 EP claimed
EP-0499349-B1 Process for preparing a degradation resistant molded pulp horticultural container CHINET CO (US) 1997-07-09 EP claimed
EP-0626379-A2 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 1994-11-30 EP claimed
EP-0087701-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS CASSELLA Aktiengesellschaft (DE) 1986-08-20 EP claimed
EP-0087701-A2 Process for the preparation of 2-chlorobenzoxazols CASSELLA Aktiengesellschaft (DE) 1983-09-07 EP claimed
EP-0626379-B1 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 2001-03-21 EP disclosed
EP-0626379-A2 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 1994-11-30 EP disclosed
EP-0626379-A2 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 1994-11-30 EP disclosed
EP-0141053-B1 METHOD FOR THE PREPARATION OF 2-CHLORBENZOXAZOLES CASSELLA Aktiengesellschaft (DE) 1987-08-19 EP disclosed
EP-0087701-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS CASSELLA Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0141053-A1 Method for the preparation of 2-chlorbenzoxazoles CASSELLA Aktiengesellschaft (DE) 1985-05-15 EP disclosed
EP-0087701-A2 Process for the preparation of 2-chlorobenzoxazols CASSELLA Aktiengesellschaft (DE) 1983-09-07 EP disclosed
EP-0044497-A2 Process for the production of heterocyclic substituted derivatives of 4-oxyphenoxy-alkane-carbonic acid HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-27 EP disclosed
US-4242495-A COATINGS, MOLDINGS, FOAMS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-30 US disclosed