Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067264 | 0.78 | MAOA (0.38) | MAOAMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL5530904 | 0.74 | MAOA (0.41) | MAOAMAOBGAAABCG2MEN1 | |
| SCHEMBL17185668 | 0.73 | MAOA (0.39) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL7757699 | 0.73 | MAOA (0.39) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL6414082 | 0.72 | MAOA (0.35) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL6199231 | 0.70 | NISCH (0.38) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL14833074 | 0.70 | HSD17B3 (0.38) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL16229965 | 0.68 | HSD17B3 (0.36) | MAOAMAOBGAAMEN1KMT2A | |
| SCHEMBL13583885 | 0.67 | KDM4E (0.37) | GAAMEN1KMT2AHSD17B3TSHR | |
| SCHEMBL3454074 | 0.67 | MAOA (0.43) | MAOAMAOBGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825192-B1 | Benzoxazolylisoindolenines | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2002-11-13 | — | — | EP | claimed |
| EP-0825192-A1 | Benzoxazolylisoindolenines | BAYER AG (DE) | 1998-02-25 | — | — | EP | claimed |
| EP-1140862-A4 | THROMBIN OR FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-0825192-B1 | Benzoxazolylisoindolenines | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2002-11-13 | — | — | EP | disclosed |
| US-6403583-B1 | ANTICOAGULANT AGENTS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS. | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-06-11 | — | — | US | disclosed |
| EP-1140862-A1 | THROMBIN OR FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039102-A1 | THROMBIN OR FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |
| EP-0825192-A1 | Benzoxazolylisoindolenines | BAYER AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| EP-0163236-B1 | BENZOXAZOLYL AND BENZOTHIAZOLYL AMINOACIDS, THEIR PREPARATION AND THEIR USE IN THE PRESERVATION OF PLANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0163236-A2 | Benzoxazolyl and benzothiazolyl aminoacids, their preparation and their use in the preservation of plants | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-04 | — | — | EP | disclosed |