Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648635 | 0.74 | HSD17B3 (0.36) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6645559 | 0.72 | MAOA (0.39) | MAOAMAOBNPC1LMNARAB9A | |
| SCHEMBL5530904 | 0.70 | MAOA (0.41) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7757699 | 0.68 | MAOA (0.39) | MAOAMAOBLMNASMN1; SMN2DPP4 | |
| SCHEMBL17185668 | 0.68 | MAOA (0.39) | MAOAMAOBLMNASMN1; SMN2DPP4 | |
| SCHEMBL8195798 | 0.67 | LIPE (0.41) | DPP8MEN1KMT2A | |
| SCHEMBL14833074 | 0.65 | HSD17B3 (0.38) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL6199231 | 0.65 | NISCH (0.38) | MAOAMAOBDPP4DPP8DPP7 | |
| SCHEMBL27426301 | 0.64 | MAOA (0.35) | MAOAMAOBNPC1LMNARAB9A | |
| SCHEMBL9067264 | 0.61 | MAOA (0.38) | MAOAMAOBNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286987-B1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | AUSTRIA WIRTSCHAFTSSERV GMBH (AT) | 2005-09-28 | — | — | EP | disclosed |
| EP-1286987-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung (AT) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094340-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | INNOVATIONSAGENTUR GESELLSCHAFT M.B.H. (AT) | 2001-12-13 | — | — | WO | disclosed |