Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772823 | 0.87 | CHRM2 (0.41) | AKT1CHRM2CHRM1PTGER1PTGER4 | |
| SCHEMBL7758293 | 0.85 | ELANE (0.38) | ELANEAKT1CHRM2CHRM1PPARG | |
| SCHEMBL7755557 | 0.82 | KMT2A (0.42) | ELANEPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7755600 | 0.81 | ALOX15 (0.42) | ELANEPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7758334 | 0.78 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL2167312 | 0.72 | CHRM2 (0.66) | ELANECHRM2CHRM1 | |
| SCHEMBL3772824 | 0.72 | ADRB2 (0.40) | AKT1CHRM2CHRM1PTGER1PTGER4 | |
| SCHEMBL27523797 | 0.72 | CHRM2 (0.57) | ELANECHRM2CHRM1 | |
| SCHEMBL7756438 | 0.70 | CHRM2 (0.36) | ELANECHRM2CHRM1PTGER1PTGER4 | |
| SCHEMBL7755059 | 0.70 | ELANE (0.44) | ELANECHRM2CHRM1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |