SCHEMBL7758399

SCHEMBL7758399

CC(C)(C)c1ccc(N(C(N)=O)C(=O)c2c(Cl)cccc2Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
GPBAR1 Q8TDU6 1/20 0.42
ALDH1A1 P00352 3/20 0.40
POLB P06746 2/20 0.40
NPC1 O15118 1/20 0.40
GLA P06280 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSD11B1 P28845 2/20 0.37
RORB Q92753 1/20 0.37
PTGS2 P35354 1/20 0.37
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NR1H4 Q96RI1 3/20 0.35
TLR7 Q9NYK1 1/20 0.35
RORC P51449 1/20 0.35
KIF11 P52732 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758363 0.86 TLR7 (0.42) NPSR1MAPTGPBAR1ALDH1A1POLB
SCHEMBL28500692 0.83 ALDH1A1 (0.41) RAB9AGAAMAPTGPBAR1ALDH1A1
SCHEMBL7759297 0.83 RAB9A (0.45) RAB9ANPSR1GAAMAPTALDH1A1
SCHEMBL28904678 0.82 POLB (0.44) NPSR1MAPTGPBAR1ALDH1A1POLB
SCHEMBL7754454 0.81 ALDH1A1 (0.39) MAPTGPBAR1ALDH1A1POLBNPC1
SCHEMBL7759289 0.81 ALDH1A1 (0.39) RAB9AGAAMAPTGPBAR1ALDH1A1
SCHEMBL7758398 0.80 GPBAR1 (0.42) MAPTGPBAR1ALDH1A1POLBTP53
SCHEMBL7760759 0.79 MEN1 (0.41) RAB9AMAPTALDH1A1POLBNPC1
SCHEMBL7759428 0.78 GPBAR1 (0.44) RAB9AGAAMAPTGPBAR1ALDH1A1
SCHEMBL28500688 0.78 RORC (0.39) MAPTGPBAR1ALDH1A1POLBTLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed