SCHEMBL7754454

SCHEMBL7754454

NC(=O)N(C(=O)c1c(Cl)cccc1Cl)c1ccc(I)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
GPBAR1 Q8TDU6 2/20 0.38
RORC P51449 2/20 0.34
POLB P06746 3/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
FEN1 P39748 1/20 0.33
NPC1 O15118 1/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.31
LMNA P02545 2/20 0.31
CYP3A4 P08684 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28500692 0.87 ALDH1A1 (0.41) ALDH1A1GPBAR1RORCPOLBTRPM8
SCHEMBL28904678 0.85 POLB (0.44) ALDH1A1GPBAR1POLBMEN1KMT2A
SCHEMBL29034050 0.85 ALDH1A1 (0.37) ALDH1A1RORCPOLBMEN1KMT2A
SCHEMBL7759289 0.84 ALDH1A1 (0.39) ALDH1A1GPBAR1RORCPOLBMEN1
SCHEMBL7760759 0.83 MEN1 (0.41) ALDH1A1RORCPOLBMEN1KMT2A
SCHEMBL28500688 0.81 RORC (0.39) ALDH1A1GPBAR1RORCPOLBMEN1
SCHEMBL7758399 0.81 RAB9A (0.45) ALDH1A1GPBAR1RORCPOLBMEN1
SCHEMBL7758398 0.81 GPBAR1 (0.42) ALDH1A1GPBAR1RORCPOLBMEN1
SCHEMBL7758363 0.81 TLR7 (0.42) ALDH1A1GPBAR1RORCPOLBMEN1
SCHEMBL7758404 0.81 TAS1R3 (0.50) ALDH1A1GPBAR1RORCMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed